Rizatriptan EP Impurity C HCl CAS 208941-96-2(free base)
| CAS No. | 208941-96-2(free base) |
| Molecular Formula | C15H19N5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rizatriptan EP Impurity C HCl is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Rizatriptan EP Impurity C HCl (CAS 208941-96-2(free base)), a pharmacopoeial impurity reference standard (molecular formula C15H19N5HCl, MW 305.81 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Rizatriptan EP Impurity C HCl (C15H19N5HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rizatriptan EP Impurity C HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H19N5 HCl |
| Molecular Weight | 305.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Rizatriptan Standards
- Rizatriptan EP Impurity G (CAS 1000673-59-5)
- Rizatriptan Dimer Impurity 3 (CAS 1016900-25-6)
- Rizatriptan impurity 01 (CAS 1030849-63-8)
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Rizatriptan Impurity 14 (CAS 110-95-2)
- Rizatriptan Impurity 4 (CAS 1135479-41-2)
- Rizatriptan Dimer (CAS 1135479-44-5)
- Rizatriptan Impurity 15 (CAS 114094-45-0)
Recommended Standards
- Mirabegron Impurity 49 (CAS CATO-C4X-103249)
- Glucosamine Sulfate EP Impurity B (CAS 13185-73-4)
- Palbociclib Impurity 94 (CAS CATO-C4X-112594)
- 5-amino-1-benzyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 905244-78-2)
- Pentylmagnesium Bromide (18% in Tetrahydrofuran, ca. 1mol/L) (CAS 693-25-4)
- tert-Butyl (3-(4-chloro-2-methylphenyl)-1,2,4-oxadiazol-5-yl)(methyl)carbamate (CAS 1383133-53-6)
- Pethidine impurity 6 (CAS CATO-C4X-22326)
- Fosfomycin Impurity 59 (CAS 25460-63-3)
- Posaconazole Impurity 123 (CAS 149882-18-8)
- Anti-Inflammatory Peptide 2 (CAS 118850-72-9)
Why CATO?
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